Androgens are responsible for the growth spurt of adolescence and for the eventual termination of linear growth, which is brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates but may cause a disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of growth process. Androgens have been reported to stimulate the production of red blood cells by enhancing the production of erythropoeitic stimulating factor. During exogenous administration of androgens,Â endogenous testosterone Â release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH).
Franklyn Prendergast has served on IDRI's Board of Directors since October of 1999. He is the Edmond and Marion Guggenheim Professor of Biochemistry and Molecular Biology and Professor of Molecular Pharmacology and Experimental Therapeutics at the Mayo Medical School. In the past, he has served as the Director of the Mayo Clinic Cancer Center and Director of the Mayo Clinic Center for Individualized Medicine and as the Chair of the Department of Biochemistry and Molecular Biology at the Mayo Clinic. He has also served on the Board of Trustees and on the Board of Governors of the Mayo Foundation. Franklyn's research focuses on structural protein biology and bioimaging and has earned him numerous honors, including an . Just Award from the American Society of Experimental Biology and the Musgrave Gold Medal of the Institute of Jamaica. As a Rhodes Scholar, Franklyn earned his BA and his MA from Oxford University. He then went on to receive his MD from the University of the West Indies, and his PhD from the University of Minnesota. He has also received honorary DSc's from Purdue University and the University of the West Indies.