Steroids from harrisonia abyssinica

Generally, there was a reduction in rectal temperature in turpentineinduced pyretic rats after treatment with methanolic stem bark extract of H. abyssinica ( Table 2 ) ( Figure 1 ). In the first hour after treatments, the rat groups treated with methanolic stem bark extract of H. abyssinica at all the dose levels (50, 100 and 150 mg/kg body weight) and with aspirin lowered the elevated temperature to %, %, % and %, respectively ( Table 2 ) ( Figure 1 ). The antipyretic activities exhibited by the extract were statistically insignificant (p ≥ ) ( Table 2 ) ( Figure 1 ) when compared to the normal control group and positive control group with the reference drug, aspirin. However, treatments at the dose level of 100 and 150 mg/kg body weights recorded antipyretic activities that were statistically significant when compared to the negative control group (p ≤ ) ( Table 2 ) ( Figure 1 ). The treatment at the dose level of 50 mg/kg body weight demonstrated antipyretic activity that was not statistically significant when compared to the negative control (p ≥ ) ( Table 2 ) ( Figure 1 ).

Steroids from harrisonia abyssinica

steroids from harrisonia abyssinica

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