Lung disease: People with this condition often develop emphysema, with
symptoms of a hacking cough, barrel-shaped chest, and difficulty breathing. If
you have this condition and smoke or are exposed to tobacco smoke, it
accelerates the appearance of emphysema symptoms and lung damage.
Liver disease: Alpha-1 antitrypsin deficiency also cause liver disease in some people with the condition, that include liver cancer, cirrhosis of the liver, an abnormally large liver (hepatomegaly), liver failure, and hepatitis. Liver damage from alpha-1 antitrypsin deficiency causes symptom of a swollen abdomen, swollen legs or feet, and jaundice.
Treatment of AATD depends upon the severity of symptoms. FDA approved drug for AATD is an orphan product called alpha-1-proteinase inhibitor (human), sold under the brand name "Prolastin."
I completely agree with you, Kyle. Whenever exogenous Testosterone is stopped – whether it was being taken for TRT or cycled for bodybuilding – some kind of ‘PCT’ (Post-Cycle Therapy) should be utilized to help ‘re-awaken’ your HPG axis after it had been shut down by Testosterone replacement or cycling. It is important to note that such PCT is NOT taken forever! The use of HCG and either Tamoxifen or Clomid will help greatly in reducing withdrawal symptoms by bolstering your body’s natural Testosterone production and greatly speeding up recovery time (the time it takes for your body to start creating its own testosterone again without any external substance).
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